As far as I know, biological defects like psychopathy, antisocial personality disorder , borderline personality disorder, and malignant narcissism, are both naturally harmful and incurable – but it’s obsessive biological defects like pedophilia, and hoarding that on top of evil and incurable, aren’t even treatable.
When I talk about eugenics, or ‘genetic pacification’ I don’t mean selective breeding as much as ‘selective weeding’.